Protein evolution of ANTP and PRD homeobox genes
نویسندگان
چکیده
منابع مشابه
Evolution of Antennapedia-class homeobox genes.
Antennapedia (Antp)-class homeobox genes are involved in the determination of pattern formation along the anterior-posterior axis of the animal embryo. A phylogenetic analysis of Antp-class homeodomains of the nematode, Drosophila, amphioxus, mouse, and human indicates that the 13 cognate group genes of this gene family can be divided into two major groups, i.e., groups I and II. Group I genes ...
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PAIRED (PRD)-like homeobox genes belong to a class of predicted transcription factor genes. Several of these PRD-like homeobox genes have been predicted in silico from genomic sequence but until recently had no evidence of transcript expression. We found recently that nine PRD-like homeobox genes, ARGFX, CPHX1, CPHX2, DPRX, DUXA, DUXB, NOBOX, TPRX1 and TPRX2, were expressed in human preimplanta...
متن کاملHomeobox Genes and the Homeobox
Most homeobox [5] genes [4] contain a 180-base-pair region called a homeodomain [6]. The homeodomain [6] portion of the protein transcript has been shown to interact with DNA in a cisregulatory fashion during the critical stages of early body plan specification and embryogenesis [7]. These sorts of interactions demonstrate the importance of regulatory genes [4] and their architectural role in t...
متن کاملDetection of homeobox genes in development and evolution.
The homeobox genes encode a family of DNA-binding regulatory proteins whose function and genomic organization make them an important model system for the study of development and differentiation. Oligonucleotide primers corresponding to highly conserved regions of Antennapediaclass homeodomains were designed to detect and identify homeobox sequences in populations of DNA or RNA by means of the ...
متن کاملConvergent evolution of clustering of Iroquois homeobox genes across metazoans.
Vertebrate and Drosophila Iroquois genes are organized in clusters of 3 genes sharing blocks of conserved regulatory sequences. Here, we report a 3-gene cluster in the basal, preduplicative chordate amphioxus. Surprisingly, however, the origin of the amphioxus cluster is independent of those in vertebrates and drosophilids. Investigation of genomic organization of Iroquois genes in other 17 met...
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ژورنال
عنوان ژورنال: BMC Evolutionary Biology
سال: 2008
ISSN: 1471-2148
DOI: 10.1186/1471-2148-8-200